Stayed here once on a business trip to Antwerpen. This is an upper scale hotel which is ok for business trips, but travelers must ride De Lijn in order to easily get into the old city or the train station. I'd much rather be nearer the action.
Directions: On the ring road, but there is a bus stop right outside the hotel with buses every 20 minutes into the city. Journey time about 15 minutes, costs 1 euro each way.