Considering the Akzent Moehringer Hof in Stuttgart?
A VT member wrote the following comment about visiting Stuttgart:
Stuttgart Hbf to Frankfurt airport by orlikins
If you happen to get the train from Stuttgart to Frankfurt Airport, you can check-in your luggage at Stuttgart train station, provided you are going on a Lufthansa flight from Frankfurt, so you dont have to worry about dragging your suitcases off the train when you get to Frankfurt airport train station, it is all taken off for you - cool eh? :)
A single ticket for this route costs ?44.60