Wait til you see the Venetian glass chandeliers!
Recently renovated, the rooms at the Columbia are larger than average (for Italy), good air conditioning which you can control, nice modern bathrooms with larger than usual shower and toiletry items including a toothbrush!, and each room I've stayed in (save one) has had a drop-dead-gorgeous, HUGE Venetian glass chandelier! There's a nice cafe/bar/breakfast room on the top floor. Breakfast in warm months will be on the open terrace filled with plants. Coffee and cappuccino are fresh made and very good. Buffet breakfast is fine, no hot items. They usually have cornetti (croissants), panini (fresh bread rolls), salami, cheese, jams, toast, canned fruit, hard boiled eggs, yogurt, cereals, juice (canned). There is almost no lobby, but there is a small sitting area in the breakfast room. Multilingual desk, and even the maids are friendly!
Their website lists a room rate that is quite high - usually you'll find a better rate on www.venere.com or www.holidaycity.com. Sometimes holidaycity shows availability when venere doesn't. Go figure.
Anyway, 160E in high season is a pretty reasonable rate. I've stayed here several times with friends - and we've always had a good experience. I once got a room I didn't like, and they moved me the next day.
Unique Quality: No views, but laying in your bed, looking up at the beautiful chandelier isn't bad! Very convenient to the train station, but toward the "good" side of town.