I merely booked this hotel because of its relatively good price and reliable brand name. The room also comes with free breakfast. But the location is not near to any tourist spot. So daily you'll have to take a 10 min bus to Termini or walk 15 min to metro Bologna. The problem with the bus is we always have problems recognizing which bus stop to get off in the night as it's dark. But the area is very safe and quiet as it's mainly residential. There's only one Italian restaurant nearby. Actually, it's best to stay near the Colosseum. Staying near the Termini is also very convenient but you'll have to make sure you can find a decent hotel as the place is rather crowded with all kinds of people.
Directions: Bus 90 or 36 from Station Termini, 10 mins. Look out for Villa Torloni and get off. Walk to Via Goriza and you'll find Via Gradisca. It's not easy to locate this hotel without a map indeed. Alternatively a taxi from the Termini is about Euro 9/-.