Considering the Residenza Flora in Florence?
A VT member wrote the following comment about visiting Florence:
Santa Maria Novella Train Station by Sonador3
I love this station. It's very convenient to the center of the city, both by walking and by city bus. They have automated ticketing machines that are super-easy to use, and there are plenty of places to get a drink or bite to eat while waiting for your train. Travelling by train is easy thanks to stations like this.