Wander, just wander by SaxonSon
Venice is a magical city, and I would spend the first evening just strolling, getting lost, enjoying the city. San Marco by night is enchanting, and there is really no street or alley or area you need to avoid for safety sake. If I was going to spend just one full day, I think I'd skip Burano. Though it is a quaint little island, if you're looking for lace you can do better price-wise in Venice itself (just beware of the asian import imposters) and there are equally enchanting vistas in Venice proper. If I had just one day, I would hit up the Frari church (Santa Maria Gloriosa dei Frari), which is a big, hulking barn of a church, w/ stunning staturary and monuments inside. Take in the Doges Palace (spring for the "Secret Itinerary") if you have time, but the main thing to do in Venice for a day is just to wander. Stop in every church you see, cross every bridge you come to, slip down every alley. It's a small town, and you won't really ever get lost. Take lots of pictures, fill your water bottle w/ wine from the taps (sfuzi), and make note of all the places you want to go to the next time you're there, when you have more time, 'cause really, once you're there, you'll vow to go back.The most amazing thing about Venice is the quietness, the absolute absence of moter vehicles and bicycles makes for an amazing absence of sound.