Public transportation by rbob
The location you have chose is very nice and very close to public transportation. You can walk one block to Church Street, where you take the J Church Street streetcar. This will take you to Market Street ( which is not far). At this intersection you can catch a bus or streetcar heading into just about every area of the city. I do not know about cost of car rental, but the public transportation will get you anyplace you want to go, unless you are planning a trip across one of the bridges. Again if you have any questions, I will be happy to reply if I can.BobSan Francisco is a beautiful city with fantastic views.