The popular access points: Ohio City/W.25th (& WestSide Market; popular place!)., Downtown, University Circle (see my must see activity tips) , North Coast Harbor (E9th St.) and Shaker Square. You get out at all other East side stops (besides UC) at your own risk; they're not eh greatest neighborhoods.
University Cirlce is mostly safe, although bundled between bad neighborhoods, so some questionable people tend to hang around. I don't recommend being out and about by the darkly lit places at night; be somewhere where there is light. Shaker Square is only getting worse (dangerous) and the actual Square is becoming slightly worn and less attractive, so, it not as 'off the beatn path sight-seer' friendly. Plans are in the works to reinvigorate it (it used to be adorable during Xmas time) but there's still some charm there as well as some retailers.
The fare I believe is now $1.75 one way, for each separate ride, (no connection tickets) and $3 for an All Day Pass, which allows you endless connections all day and evening until 3am from time of purchase. There are family/group fares a well. Bicycles are permitted on the cars only during non-rush hour times (see site for times). There was recently a mjaor change in the fare structure, and I'm still trying to figure it out, since their website is a bit vague. Calling them for clarification would be a good idea.


