Art in its most direct state
This a bit ambiguous "off-the-beaten-path" tip. Litteraly it depends on the "point of view". On the side this picture was taken is the modern building of the Senat and some other monstrosity representing a bank and/or the UN. The opposite side is hugged by a slum, a fact that almost automatically makes it of the beaten path since most of the travel guides keep the right to inform you to stay off similar communities.

Very old Paraguayan tram
AFW summer 06
Asuncion graffiti
Palacio de Gobierno