If you do not have a car, the you can catch the bus down to Margaret River.
South West Coaches leave from the Perth Esplanade Bus Port every day and the price is quite cheap.
Link to the site for price and booking is below.
Updated Feb 19, 2011
Website: https://secure.jbs.com.au/veoliatransportwa/bookingsexpress.aspx
Margaret River is located a couple hours south of Perth on the coast of Western Australia.
Perth, Western Australia is unique for many different reasons, but in particular, this city's airport is truly the most isolated international city on Earth. It is very difficult to reach Perth by Air, although it is constantly being made easier through multiple international carriers creating flights here.
Western Australia's airports are actually equal flying time to Singapore as Sydney. Each being a 5 hour flight from this isolated city!
Perth however is a major launching pad for alot of Southern Hemisphere Australian travel, housing the international legs of Air New Zealand, Air Mauritius and South African Airways. Perth also serves Asia with Emirates, Cathay Pacific, Royal Brunei, Garuda, Singapore, Thai, Tiger Airways and of course Qantas.
Written Jul 28, 2007
Website: http://www.perthairport.com
Driving to Margaret River is dead easy. Basically from wherever you are staying in Perth, get onto Freeway South and follow it right to the end where it becomes Safety Bay Road. Turn off Safety Bay Road into Ennis Avenue and keep following this (even through all its name changes) until you get to Bunbury. From here the road is pretty well signposted to Busselton. However when you near Busselton there is a big roundabout that leads to the Busselton Bypass. Take that route and keep going until you get to the end, turn left at the Bussell Highway and keep going till you hit town.
So really you just keep driving straight ahead until you are forced to make a choice and then always turn towards Busselton! Easy.
Written Dec 19, 2006
TransWA can get you to Margaret River. If this is your only mode of transport then it's a great facility, however the trip will take 5 hours, and you can drive yourself there in 3 hours. So it depends on how long you are going for as to whether you want to spend that amount of timie on a bus. An onscreen video is screened and there is a pit stop along the way.
The website is handy. You can find out all sorts of information about the trip and book your tickets online. And the trip only costs about $33 each way.
Written Oct 26, 2006
Phone: 1300 6622 05
Website: http://www.transwa.wa.gov.au/Default.aspx
Margaret River is over 3 hours drive from Perth using South Western Highway (Route 20) and then Bussell Highway (Route 10) out of Busselton which runs directly to Margaret River.
Written Nov 15, 2002
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Reviews and photos of Margaret River attractions posted by real travelers and locals. The best tips for Margaret River sightseeing.

Margaret River is over 3 hours drive from Perth using South Western Highway (Route 20) and then Bussell Highway (Route 10) out of Busselton which runs directly...
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1

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Hub of the area known colloquially as "Down South" by Western Australians, the little town of Margaret River has something for everyone. Once a small timber town, just a street lined with mill workers...
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Note: Underlined = tip below In our previous trip to rural Western Australia, we had considered a trip to Margaret River (MR), but as it was Easter time and the famous surf carnival would have been...
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Update 27th August 2007 - The Cape to Cape Walk was recently featured on Channel 7's "The Great Outdoors" If you have the time and inclination you can walk from Cape Naturaliste in the north to Cape...
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