The Colon Free Trade Zone is a major shopping area in Colón, Panama. It offers duty-free products and services for import, storage, and re-export to countries around the world.

Fort San Lorenzo is a historical site built in 1595 by King Phillip II. It offers views of the Chagres River and is known for its well-preserved moat and cannons, some of which are British-made.

Gatun Locks are a vital part of the Panama Canal that raise ships 30 meters from the Caribbean Sea to Lago Gatún. These massive lock chambers, which stretch 3 kilometers, are large enough to hold the Titanic with room to spare.

Port Colon 2000 is located in Manzanillo Bay near the Panama Canal. It offers shopping, dining, and entertainment for cruise-ship travelers.

Agua Clara Locks is a part of the Panama Canal, located in Colon. It allows ships to pass through the Isthmus of Panama and features a visitor center with great views of the locks.