You can reach Butrint from Saranda. The 14 km road is very narrow, mostly single lane and in some places carved in steep slopes and it overhangs the lake Butrint. The road was built in 1959 for a visit by the Soviet leader Nikita Khrushchev and it hasn’t been touched again since though the traffic has increased dramatically with the increasing interest for Butrint. It is can be scary to cross another vehicle, especially if it is a bus, not to speak of two busses crossing ! A 2 lanes highway is planned and should be finished in 2010 but in may 2009 I have not seen any road work. May be the new road does not pass in the same place than the old one.
From Greece, a ferry links Kérkira (Corfu) to Saranda. Greek Nissaki and Kassiopi are just in front of Buthrint, across the Straits of Corfu.
The third way to reach Butrint is the one we chose in 2007, driving from Sagiada. I have described it on my Konispol page
Butrint is in the southern most tip of Albania. It is a few kilometres away from the Greek border, on the other side of the river Pavllo. A custom office has only been opened between Sagiada (Greece) and Konispol (Albania) in 2005. I have given the report of our travl on this road on my Konispol page.
There is a bus that runs between Saranda and the villages past Butrint, but it's a pretty rickety old thing, and I never used it so can't comment. Your best bet is probably to find a taxi, but you'll find yourself a cheaper one if you leave the port and walk into Saranda town or to the main road on the far side of the bay of Saranda* (15 minutes). I remember we were charged 1000 leke from Saranda to Ksamili, and Butrint is only a little further, but it's probably best to agree a price for the day as it is difficult to find taxis in Butrint in the afternoon. A good daily rate would be about 5000 leke.
*The picture shows the best place to get a taxi from in Saranda.
Whatever means of transport you decide on to get to Butrint from Sarande, be warned, the road follows the cliff edge and is only a little wider than a single lane. It's quite twisty, especially once you get past Ksamili, so meeting a vehicle coming the other way can be quite a hair raising experience. You will notice that everyone beeps their horn when approaching a corner - to let anyone coming know of their approach. Of course, they're driving so fast anyway that it probably won't make any difference...
If you want to explore the area across the Vivari strait from Butrint itself, for example to visit the Triangular Fortress, you'll need to use the pontoon ferry. It's seemingly free to use, and the wait isn't too long for it to get from one side to the other and back again.