Biking is the main means of transportation in Ferrara.
Apparently only city residents can park on the streets, so if you are driving, try to find the nearest car park. We left our car at the "Parcheggio CENTRO STORICO", which was a couple of blocks away. € 4.50 for 24hrs.
If you have luggage, it's advisable to leave them first at the hotel before parking.
On a quick note, when my husband went there to get the car, he was approached by 2 guys asking for money. Just in case (if you know what I mean...), he gave them € 0.50.
The number of people who ride a bicycle is much higher in Ferrara than in many Italian middle-sized cities. However, this can prove a danger for those who are not accustomed to the way the Ferrarese ride their bikes.
Cyclists feel as the masters of the streets, they do not break when they get close to a pedestrian, they ignore that all bikes have a bell and, what irritates me the most, they ride across pedestrian streets, as they would ride in normal streets!
So, when walking across the nice streets of Ferrara, look continuously around yourself! A bike may invest you when you wouldn't expect it! Ferrarese bikes are as dangerous as cars in the rest of the country.
As a 'general' rule of thumb, attractions are closed in Italy on Mondays. Be sure to check ahead to confirm that what you have traveled thousands of miles to see, is going to be open to the public.
Ferrara is a dead loss on Mondays. The castello, which we particularly did want to view, closes on Mondays. Strangely, the Tourist Information Centre was open, and open after 2pm too (usually close from 1pm-3:30). However, they were not too forth coming in information, nor suggestions of other places to go.
Living here, I can assure you that Ferrara is definitely a safe city. If you stay downtown, in the Castle area, or near Piazza Ariostea or Palazzo Diamanti you can basically walk alone at 3am at night without any fear.
Zones to avoid: definitely avoid staying near the train station, or in the north-western part of town (like, the western part of via Modena). Since you're a tourist here, I don't think you'd like to stay in the only unsafe part of town, do you?
So to sum it up again: you're perfectly safe within 1,5 km from the center, just avoid the train station at night (during the day it's fine, don't worry). Apart from that, enjoy your staying.