Walking, Rome

Ok, I've said this before but walking is usually the best way to get around and to see the city (not just the "sights" but the city itself).
Plus, getting lost is how you find those really interesting places - or, at least, get interesting stories.
That said, there are buses and trams in Rome. The trams are pretty easy - I take the tram from my apartment up to Largo Argentina on occasion.
The buses I still haven't really used at all.
Really, though, Rome is a good city to walk in, probably more than some others (like Washington D.C. for one).

Arm yourself with a detailed street map, not the general overview handed out free at tourist offices. Most hotels hand out a pretty good version at their front desks.

The bulk of ancient, Renaissance, and baroque Rome (as well as the train station) lies on the east side of the Tiber River (Fiume Tevere), which meanders through town. However, several important landmarks are on the other side: St. Peter's Basilica and the Vatican, the Castel Sant'Angelo, and the colorful Trastevere neighborhood.

The city's various quarters are linked by large boulevards (large, at least, in some places) that have mostly been laid out since the late 19th century. Starting from the Vittorio Emanuele Monument, a controversial pile of snow-white Brescian marble that's often compared to a wedding cake, there's a street running practically due north to Piazza del Popolo and the city wall. This is Via del Corso, one of the main streets of Rome--noisy, congested, always crowded with buses and shoppers, and called simply "Il Corso." To its left (west) lie the Pantheon, Piazza Navona, Campo de' Fiori, and the Tiber. To its right (east) you'll find the Spanish Steps, the Trevi Fountain, the Borghese Gardens, and Via Veneto.

Finding an address in Rome can be a problem because of the narrow streets of old Rome and the little, sometimes hidden piazze (squares). Numbers usually run consecutively, with odd numbers on one side of the street and even numbers on the other. However, in the old districts the numbers will sometimes run consecutively up one side of the street to the end, then back in the opposite direction on the other side. Therefore, no. 50 could be opposite no. 308.

Walk, go walking to everywhere. You'll enjoy of what you'll find every few streets, and you'll be closer to the romans' everyday life. Mix with them. As less tourist you see at a given place, as real and better it will be your experience at that place. Take your time. Take as much time as you can

Allright, now that you´re IN the city at the spot where you want to begin.... just start walking!!!
This is absolutely the best way to get into the heart of Rome. You will walk from one beautiful excavation to the next immense ancient building. Make sure you plan to do the big ones before you start otherwise you will wonder around for ever.

Getting around Rome is basically on foot as most sights are very close.The streets are mainly clogged with traffic and driving would be frightening.Renting a motor bike would be ok as long as you are very careful.When walking,,,be very careful when you cross a road as traffic will not stop.I found walking around Rome the nicest and easiest way to see things and i was surprised just now close most sights were.

The best way to get around is to walk the city. Rome is so much smaller than London or Paris. There really is no need to take any form of transportation besides your legs & feet if you don't have children. If you are staying for awhile or have a definate destination outside the walls then walking will be good enough to get around. I did take the underground to see San Paolo Fuori le Mura. It was very easy to do. You can either buy a ticket from a newsstand or at the station. Try to make sure you have small change with you. Traffic is a constant in Rome, like you wouldn't assume that in a city of nearly 3 million and who knows how many tourists.

On foot! Don't use a taxi. However, if time is limited, an organised day trip taking in The Colisseum and Capitoline will take care of the more difficult to access places. Crossing the road can be a nightmare in Rome, you have to be foreceful about it, and trust that the crazy drivers would rather not damage their cars by driving into you!

Well...as usual...I mostly walked, the best way to see a city. In Rome there is history around every corner. I also used the subway. Vespas can also be rented...but they can be dangerous! I saw two accidents while I was in Rome involving vespas.