On Friday and Saturday nights Barrique is the most popular place to hang out for the locals. There is an excellent DJ, and sometimes live music. They have a large drink selection, and the staff is wonderfully friendly and helpful. People spill out of the bar and form a huge crowd on the street. It can get really busy, but is fun if you are looking for an energetic environment. Also a good place for taking an apertif on week day evenings.
The nightlife can be fun in Umbria and Orvieto. Visit http://www.visitorvieto.com Visit Orvieto information for nightlife, Enoteca's, restaurants and the theatre including festival information in town!