Titus canyon is very impressive and you can drive it. Some parts are very narrow but there were a lot of cactus which were in flowers when we visited. See my flowers, many of the cactus were shot in Titus canyon.
The one-way dirt road that goes through Titus Canyon starts at Hwy. 374 in the Nevada desert. The road is 28 miles long and is suitable only for four-wheel-drive vehicles or vehicles with high clearance. Do follow this indication, the road is in really bad shape and you can damage your car (not talking about getting stuck there and blocking everyone that comes behind you). It's one of the most spectacular drives in the park, with gorgeous narrows, twisted rock formations, indian petroglyphs and an interesting geology. Near the beginning of Titus Canyon lies the ghost town of Leadfield which experienced a short mining boom of about 6 months in 1925.
Titus Canyon has it all - rugged mountains, colorful rock formations, a ghost town, petroglyphs, wildlife and spectacular narrows. The 27 mile drive through the canyon is one-way from the east. The dirt road is rough, steep and narrow. Although a 4x4 is recommended, most standard vehicles with high clearance should have no problems if you take it slow.
This is the only canyon accessible to motor vehicles. Its spectacular walls make it one of Death Valley's major attractions. Whether you hike or drive, be careful to watch for oncoming traffic.