Shockoe Bottom, Richmond
Off the beaten path a bit from downtown Richmond, but within walking distance of the Virginia State Capital, is an area of Richmond known as Shockoe Bottom. This area of Richmond is known as one of the oldest neighborhoods in Richmond, and most of this land was owned by Colonel William Mayo in the 1700's. As far as I can trace, Colonel Mayo is only a distant relative to Colonel Mustard of Clue, the board game, fame.
The area here is in the rebuilding process from a devastating hurricane which left it flooded in 2004, but signs of revitalization are definitely seen. In fact, in an effort to get Shockoe Bottom on the right track to being removed from "Off the Beaten Path", area legislators have even created a Myspace page for Shockoe Bottom.