4 Star Hotels in Key West

Not Just Any Hotel – Only the Best 4 Star Hotels in Key West, Selected for You!

Key West
Jul 22, 2025 - Jul 23, 2025
2 adults, 1 room
Find
Price per night:
Up to $100
$100 - 200
From $200
Rating:
Excellent 9+
Very good 8+
Good 7+
All ratings
Star rating:
5-stars
4-stars
3-stars
Unrated
View map · 1.0 mi City Centre
From
79US$ /per night
View map · 1.3 mi City Centre
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224US$ /per night
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291US$ /per night
View map · 1.8 mi City Centre
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310US$ /per night
View map · 2.2 mi City Centre
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197US$ /per night
8.8
Excellent (1)
View map · 1.1 mi City Centre
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201US$ /per night
View map · 1.1 mi City Centre
From
205US$ /per night
4
Good (1)
View map · 2.1 mi City Centre
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123US$ /per night
View map · 0.4 mi City Centre
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159US$ /per night
View map · 0.9 mi City Centre
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271US$ /per night
View map · 2.0 mi City Centre
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250US$ /per night
View map · 1.6 mi City Centre
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319US$ /per night
View map · 1.4 mi City Centre
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1265US$ /per night
View map · 1.3 mi City Centre
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365US$ /per night
View map · 1.5 mi City Centre
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302US$ /per night
View map · 1.2 mi City Centre
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159US$ /per night
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237US$ /per night
View map · 1.0 mi City Centre
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164US$ /per night
View map · 0.8 mi City Centre
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180US$ /per night
View map · 1.5 mi City Centre
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369US$ /per night
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244US$ /per night
View map · 0.6 mi City Centre
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149US$ /per night
View map · 1.1 mi City Centre
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156US$ /per night
View map · 2.8 mi City Centre
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154US$ /per night
View map · 0.9 mi City Centre
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199US$ /per night
View map · 1.2 mi City Centre
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299US$ /per night
View map · 1.0 mi City Centre
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279US$ /per night
View map · 1.2 mi City Centre
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309US$ /per night
View map · 1.1 mi City Centre
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94US$ /per night
View map · 1.2 mi City Centre
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399US$ /per night
View map · 0.6 mi City Centre
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161US$ /per night
View map · 1.4 mi City Centre
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258US$ /per night
View map · 1.4 mi City Centre
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199US$ /per night
View map · 0.6 mi City Centre
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123US$ /per night
View map · 0.8 mi City Centre
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199US$ /per night
View map · 1.3 mi City Centre
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199US$ /per night
View map · 1.2 mi City Centre
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64US$ /per night
View map · 0.9 mi City Centre
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417US$ /per night
View map · 1.1 mi City Centre
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303US$ /per night
View map · 0.9 mi City Centre
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118US$ /per night
View map · 1.1 mi City Centre
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114US$ /per night
View map · 1.1 mi City Centre
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329US$ /per night
View map · 1.2 mi City Centre
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114US$ /per night
View map · 0.6 mi City Centre
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226US$ /per night
View map · 0.9 mi City Centre
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199US$ /per night
View map · 1.4 mi City Centre
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285US$ /per night
View map · 1.1 mi City Centre
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210US$ /per night
View map · 0.6 mi City Centre
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398US$ /per night
View map · 0.8 mi City Centre
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139US$ /per night
View map · 0.9 mi City Centre
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347US$ /per night
View map · 1.3 mi City Centre
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142US$ /per night
View map · 1.1 mi City Centre
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2257US$ /per night
View map · 1.3 mi City Centre
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4595US$ /per night
View map · 1.9 mi City Centre
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882US$ /per night
View map · 1.3 mi City Centre
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363US$ /per night
View map · 1.1 mi City Centre
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447US$ /per night
View map · 1.2 mi City Centre
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159US$ /per night
View map · 1.3 mi City Centre
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768US$ /per night
View map · 1.0 mi City Centre
From
210US$ /per night
View map · 0.9 mi City Centre
From
327US$ /per night

Discover Your Perfect Stay

Key West, with its vibrant culture, stunning sunsets, and laid-back atmosphere, is a tropical paradise that attracts travelers from around the globe. For those seeking a perfect blend of comfort and luxury, 4 star hotels in Key West offer an ideal accommodation option. These properties not only provide excellent amenities but also immerse guests in the region's unique charm and character.

When planning your getaway, consider staying at one of the premier 4 star hotels that boast breathtaking waterfront views and lavish facilities. Many of these hotels feature on-site dining options, luxurious spas, and easy access to local attractions, allowing you to indulge in the best of what Key West has to offer. Additionally, the personalized service and attention to detail found in these establishments ensure that every moment of your stay is memorable.

Whether you're looking to unwind by the pool, explore the vibrant nightlife, or soak up the local history, 4 star hotels in Key West cater to a variety of interests. From boutique hotels that reflect the island's rich heritage to modern resorts with all the contemporary amenities, you’ll find the perfect accommodation to suit your needs. Prepare for an unforgettable experience as you discover the perfect balance of relaxation and adventure in this stunning destination.

Name of hotel Accommodation Rating Price, $
Ocean Key Resort & Spa, A Noble House Resort

8.5 / 10

(111 Reviews)

From 369US$
Opal Key Resort & Marina

8.4 / 10

(1287 Reviews)

From 236US$
The Marker Waterfront Resort

8.7 / 10

(600 Reviews)

From 312US$
8.5
Very good (111)

Ocean Key Resort & Spa, A Noble House Resort

4
Zero Duval Street
Ocean Key Resort & Spa captures the essence of Key West luxury among the 4 star hotels in Key West with its stunning oceanfront location. This resort features a world-class spa, where guests can indulge in rejuvenating treatments inspired by the sea. Rooms come equipped with modern conveniences and private balconies that overlook the tranquil waters, creating a picturesque setting for relaxation. For dining, the resort offers delicious seafood at Sunset Pier, complemented by spectacular sunset views. Visitors can also enjoy amenities such as a poolside bar and a stunning infinity pool that feels like an extension of the ocean. Embrace the tranquil atmosphere and upscale offerings at Ocean Key Resort & Spa.

From

369US$ /per night
8.4
Very good (1287)

Opal Key Resort & Marina

4
245 Front Street
Opal Key Resort & Marina stands out among the 4 star hotels in Key West with its prime location along the waterfront, offering breathtaking views of the Gulf of Mexico. Guests can enjoy the resort's immaculate pools and lush gardens, creating a serene oasis in the center of the island. The spacious rooms are elegantly decorated, equipped with modern amenities, and offer private balconies to soak in the stunning vistas. Dining options at Opal Key include a variety of delectable seafood dishes at the on-site restaurant. The resort's close proximity to popular attractions like Mallory Square makes it an ideal choice for those looking to explore the local culture. Experience the blend of luxury and laid-back charm that defines this exceptional hotel.

From

236US$ /per night

4 Star Hotels in Key West

When it comes to experiencing the ultimate relaxation in Key West, waterfront retreats take center stage among the 4 star hotels in Key West. These hotels not only offer stunning views but also provide guests with the opportunity to indulge in tropical breezes and scenic sunsets. The ambiance is often complemented by stylish designs, upscale amenities, and easy beach access, ensuring an unforgettable escape. Whether you prefer lounging by the pool with ocean views or exploring the nearby waterfront activities, these hotels are ideal for a rejuvenating retreat. From charming boutique stays to expansive resorts, you’ll find a perfect fit for your dream vacation. Discover the luxury of sun, sand, and sea at these exquisite properties.

8.7
Excellent (600)

The Marker Waterfront Resort

4
200 William Street
The Marker Waterfront Resort is another gem among the 4 star hotels in Key West, located just steps from the vibrant Duval Street. With its three inviting pools and beautifully landscaped courtyards, this resort offers a refreshing escape for guests of all ages. The accommodations feature luxurious furnishings, modern amenities, and a blend of island-inspired decor, promising comfort and style. Guests can dine at the on-site restaurant, which emphasizes fresh, local ingredients and offers a delightful dining experience. The resort also provides easy access to watersports, making it perfect for adventure enthusiasts. Enjoy the vibrant atmosphere and impeccable service at this lovely waterfront property.

From

312US$ /per night

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